The effective function of circular RNA in colorectal cancer
نویسندگان
چکیده
Abstract Colorectal cancer (CRC) is the 3rd most common type of worldwide. Late detection plays role in one-third annual mortality due to CRC. Therefore, it essential find a precise and optimal diagnostic prognostic biomarker for identification treatment colorectal tumorigenesis. Covalently closed, circular RNAs (circRNAs) are class non-coding RNAs, which can have same function as microRNA (miRNA) sponges, regulators splicing transcription, interactors with RNA-binding proteins (RBPs). circRNAs been investigated specific targets These also linked metastasis, proliferation, differentiation, migration, angiogenesis, apoptosis, drug resistance, illustrating importance understanding their involvement molecular mechanisms development progression In this review, we present detailed summary recent findings relating dysregulation potential
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ژورنال
عنوان ژورنال: Cancer Cell International
سال: 2021
ISSN: ['1475-2867']
DOI: https://doi.org/10.1186/s12935-021-02196-0